The back cover picture shows one of the strategies for counteracting the cold stress adopted from the Arctic isolate Colwellia psychrerythraea 34H. Bacteria thriving in cold habitats have developed various mechanisms to avoid the cells freezing. Some of these strategies involve outer‐membrane (OM) molecules such as lipopolysaccharides. These molecules are embedded in the OM through their glycolipid portion and, together with phospholipids, are devoted to maintaining the fluidity of the membrane. We have completely characterised the lipid A portion of the lipopolysaccharide from Colwellia, a contribution to the elucidation of the structure–function relationship for these molecules isolated from psychrophiles. More information can be found in the full paper by A. Casillo, M. M. Corsaro et al. on page 1845 in Issue 18, 2017 (DOI: 10.1002/cbic.201700287).

中文翻译：

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封面特征：来自冷适应细菌的异常脂质A：详细的结构表征（ChemBioChem 18/2017）

封底图片显示了应对北极分离株Collwellia psychrerythraea 34H所采取的冷应激策略之一。在寒冷的栖息地繁衍的细菌已经发展出各种机制来避免细胞冻结。其中一些策略涉及外膜（OM）分子，例如脂多糖。这些分子通过其糖脂部分包埋在OM中，并与磷脂一起致力于维持膜的流动性。我们已经完全鉴定了来自Colwellia的脂多糖的脂质A部分，有助于阐明从嗜冷性分子中分离出的这些分子的结构-功能关系。可以在A. Casillo，M. M. Corsaro等人的全文中找到更多信息。就在第18期，2017年1845页（：10.1002 / cbic.201700287 DOI）。