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Synthetic lethality screens point the way to new cancer drug targets
Nature Reviews Drug Discovery ( IF 122.7 ) Pub Date : 2017-09-15 , DOI: 10.1038/nrd.2017.165
Asher Mullard

A resurgence in synthetic lethality screening, enabled by CRISPR gene editing, is unlocking targeted drugs for patients with cancerous loss-of-function mutations.

中文翻译:

合成杀伤力筛查为新的癌症药物靶标指明了道路

通过CRISPR基因编辑实现的合成致死性筛查的兴起,正在为具有癌症功能丧失突变的患者提供靶向药物。
更新日期:2017-09-04
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