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Cancer: Inhibiting ROCK in neuroblastoma
Nature Reviews Drug Discovery ( IF 122.7 ) Pub Date : 2017-08-11 , DOI: 10.1038/nrd.2017.160 Crunkhorn Sarah
Nature Reviews Drug Discovery ( IF 122.7 ) Pub Date : 2017-08-11 , DOI: 10.1038/nrd.2017.160 Crunkhorn Sarah
Neuroblastoma is a childhood tumour originating from the neural crest, for which treatment options are limited. Dyberg et al. report a high frequency of mutations in genes associated with RHO–RAC signalling in human neuroblastoma samples. Increased expression of the downstream RHO-activating kinase ROCK2 was
中文翻译:
癌症:抑制神经母细胞瘤中的ROCK
神经母细胞瘤是一种起源于神经c的儿童期肿瘤,治疗选择有限。Dyberg等。报告了人类神经母细胞瘤样品中与RHO-RAC信号相关的基因中的高频率突变。下游RHO激活激酶ROCK2的表达增加
更新日期:2017-09-04
中文翻译:
癌症:抑制神经母细胞瘤中的ROCK
神经母细胞瘤是一种起源于神经c的儿童期肿瘤,治疗选择有限。Dyberg等。报告了人类神经母细胞瘤样品中与RHO-RAC信号相关的基因中的高频率突变。下游RHO激活激酶ROCK2的表达增加