5-hydroxymethyl furfural (HMF) is a bio-based platform chemical with high potential. The as-synthesized Nb-SBA-15 catalysts with mesoporous structures showed high catalytic performance for the conversion of carbohydrates to HMF in a “one-pot” process using biphasic conditions of THF/H₂O-NaCl as the solvents. Nb-SBA-15 catalysts with different Si/Nb ratios were characterized by analytical techniques such as XRD, elemental analysis, SEM, TEM, N₂ adsorption, NH₃-TPD UV–vis DRS, Raman and Pyridine-FTIR. It was found that the acidity of Nb-SBA-15 catalysts could be tuned by modifying addition amount of niobium. The effects of reaction conditions, including temperature, time, and catalyst loading, on the conversions of carbohydrates and the yields of HMF were also investigated. The studies showed that Nb-SBA-15-40 catalysts which Si/Nb ratio is 40 gave the best yields of HMF due that Nb-SBA-15-40 had more niobium species in the SBA-15 silica framework and the mononuclear tetrahedral NbO₄. Under the optimized conditions, the yield of HMF could reach 61.8% at 93.5% glucose conversion and 50.7% at 94.0% cellulose conversion, respectively. Moreover, its catalytic performance was largely retained after 10 recycles in glucose conversion reaction vindicating its good catalytic stability.

5-羟甲基糠醛（HMF）是一种具有高潜力的生物基平台化学品。初生的具有介孔结构的Nb-SBA-15催化剂在使用THF / H ₂ O-NaCl两相条件的“一锅法”过程中显示出将碳水化合物转化为HMF的高催化性能。通过XRD，元素分析，SEM，TEM，N ₂吸附，NH ₃等分析技术对不同Si / Nb比的Nb-SBA-15催化剂进行了表征。-TPD紫外-相对于DRS，拉曼光谱和吡啶-FTIR。发现可以通过改变铌的添加量来调节Nb-SBA-15催化剂的酸度。还研究了反应条件（包括温度，时间和催化剂负载量）对碳水化合物转化率和HMF收率的影响。研究表明，Si / Nb比为40的Nb-SBA-15-40催化剂产生的HMF的产率最高，这是因为Nb-SBA-15-40在SBA-15二氧化硅骨架和单核四面体NbO中具有更多的铌物种₄。在最佳条件下，葡萄糖转化率为93.5％时，HMF的收率可达到61.8％；纤维素转化率为94.0％时，HMF的收率可达到50.7％。此外，在葡萄糖转化反应中循环10次后，其催化性能得到了很大的保留，证明了其良好的催化稳定性。