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Alectinib versus Crizotinib in Untreated ALK-Positive Non–Small-Cell Lung Cancer
The New England Journal of Medicine ( IF 96.2 ) Pub Date : 2017-06-06 , DOI: 10.1056/nejmoa1704795
Solange Peters , D. Ross Camidge , Alice T. Shaw , Shirish Gadgeel , Jin S. Ahn , Dong-Wan Kim , Sai-Hong I. Ou , Maurice Pérol , Rafal Dziadziuszko , Rafael Rosell , Ali Zeaiter , Emmanuel Mitry , Sophie Golding , Bogdana Balas , Johannes Noe , Peter N. Morcos , Tony Mok

As compared with crizotinib, alectinib showed superior efficacy and lower toxicity in primary treatment of ALK-positive NSCLC. (Funded by F. Hoffmann–La Roche; ALEX ClinicalTrials.gov number, NCT02075840.)

中文翻译:

艾乐替尼与克唑替尼治疗未治疗的ALK阳性非小细胞肺癌

与克唑替尼相比,艾乐替尼在ALK阳性NSCLC的初级治疗中显示出更高的疗效和更低的毒性。(由F. Hoffmann–La Roche资助; ALEX ClinicalTrials.gov编号,NCT02075840。)
更新日期:2017-08-31
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