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Cerebral venous thrombosis
Nature Reviews Neurology ( IF 28.2 ) Pub Date : 2017-08-18 00:00:00 , DOI: 10.1038/nrneurol.2017.104
Suzanne M. Silvis , Diana Aguiar de Sousa , José M. Ferro , Jonathan M Coutinho

Cerebral venous thrombosis (CVT) is an important cause of stroke in young adults. Data from large international registries published in the past two decades have greatly improved our knowledge about the epidemiology, clinical manifestations and prognosis of CVT. The presentation of symptoms is highly variable in this disease, and can range from a patient seen at the clinic with a 1-month history of headache, to a comatose patient admitted to the emergency room. Consequently, the diagnosis of CVT is often delayed or overlooked. A variety of therapies for CVT are available, and each should be used in the appropriate setting, preferably guided by data from randomized trials and well-designed cohort studies. Although deaths from CVT have decreased in the past few decades, mortality remains ~5–10%. In this Review, we provide a comprehensive and contemporary overview of CVT in adults, with emphasis on advancements made in the past decade on the epidemiology and treatment of this multifaceted condition.

中文翻译:

脑静脉血栓形成

脑静脉血栓形成(CVT)是年轻人中风的重要原因。在过去的二十年中,来自大型国际注册机构的数据大大提高了我们对CVT的流行病学,临床表现和预后的了解。症状的表现在该疾病中变化很大,范围从在诊所有头痛1个月病史的患者到进入急诊室的昏迷患者。因此,CVT的诊断通常被延迟或忽略。有多种用于CVT的疗法,每种疗法应在适当的环境中使用,最好以随机试验和精心设计的队列研究数据为指导。尽管在过去的几十年中CVT导致的死亡人数有所减少,但死亡率仍然约为5-10%。在这篇评论中,
更新日期:2017-08-31
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