Recent evidence supports a functional connection between gut microbiota and the nervous system. Here the authors show that gut microbiota plays a critical role in the development of chemotherapy-induced pain. This role of the microbiota is likely mediated, in part, by Tlr4 expressed on hematopoietic cells, including macrophages.

中文翻译：

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肠道菌群对于诱导化学疗法引起的疼痛至关重要

最近的证据支持肠道菌群和神经系统之间的功能联系。在这里，作者表明肠道菌群在化学疗法诱发的疼痛的发展中起着至关重要的作用。微生物群的这种作用可能部分地由在包括巨噬细胞的造血细胞上表达的Tlr4介导。