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Organochlorine compounds in the adipose tissue of urban and rural women who gave birth by cesarean delivery in northern Turkey
Toxicology Research ( IF 2.1 ) Pub Date : 2017-05-17 00:00:00 , DOI: 10.1039/c7tx00111h
Yavuz Kursad Das 1, 2, 3, 4, 5 , Davut Guven 3, 4, 5, 6, 7 , Dilek Guvenc 1, 2, 3, 4, 5 , Orhan Tokur 1, 2, 3, 4, 5 , Abdurrahman Aksoy 1, 2, 3, 4, 5
Affiliation  

In this study, the levels of a group of organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs) in the adipose tissue of women living in northern Turkey who gave birth by cesarean delivery were investigated. Sixty subcutaneous samples were collected in 2013 from women in urban (30) and rural (30) areas. The levels of nine OCPs, namely α-hexachlorocyclohexane (HCH), β-HCH (lindane), γ-HCH, hexachlorobenzene (HCB), aldrin, and dichlorodiphenyltrichloroethane (DDT) and its metabolites, 2,4′-dichlorodiphenyldichloroethylene (DDE), 4,4′-DDE, 2,4′-DDT, 4,4′-DDT, and 16 PCBs, PCB-28, -52, -70, -74, -81, -99, -101, -118, -138, -153, -156, -170, -180, -183, -187 and -208, were investigated with a gas chromatograph equipped with an electron capture detector (GC-ECD). β-HCH was detected in nine samples (mean 23.70 ± 4.24 ng g−1 of fat) and γ-HCH was detected in six samples (mean 41.88 ± 12.41 ng g−1 of fat). HCB was detected in five samples (mean 30.97 ± 14.31 ng g−1 of fat), 2,4′-DDT in one sample (5 ng g−1 of fat), 4,4-DDT in two samples (mean 6.70 ± 0.42 ng g−1 of fat), 2,4′-dichlorodiphenyldichloroethylene in three samples (mean 6.27 ± 0.42 ng g−1 of fat), PCB-28 in six samples (mean 10.03 ± 7.79 ng g−1 of fat), PCB-81 in one sample (7.60 ng g−1 of fat) and PCB-118 in one sample (10.20 ng g−1 of fat). In total, organochlorine compounds were detected in 12 (40%) of rural and 12 (40%) of urban women. These results are an indication of the level of organochlorine compounds in the environment where the subjects of the study lived.

中文翻译:

土耳其北部剖宫产分娩的城市和农村妇女脂肪组织中的有机氯化合物

在这项研究中,调查了居住在土耳其北部的剖宫产妇女的脂肪组织中的一组有机氯农药(OCPs)和多氯联苯(PCBs)的水平。2013年,从城市(30)和农村(30)地区的女性中收集了60个皮下样本。九种OCP的含量为α-六氯环己烷(HCH),β-HCH(林丹),γ-HCH,六氯苯(HCB),艾氏剂和二氯二苯基三氯乙烷(DDT)及其代谢产物,2,4'-二氯二苯基二氯乙烯(DDE) ,4,4'-DDE,2,4'-DDT,4,4'-DDT和16个PCB,PCB-28,-52,-70,-74,-81,-99,-101,-118用配备有电子捕获检测器(GC-ECD)的气相色谱仪研究了-138,-153,-156,-170,-180,-183,-187和-208。在9个样品中检测到β-六氯环己烷(平均23.70±4.24 ng g-1的脂肪)和γ-HCH在六个样本(平均41.88±12.41毫微克克检测-1的脂肪)。在五个样本中检测到HCB(平均30.97±14.31 ng g -1脂肪),在一个样本中检测到2,4'-DDT(5 ng g -1脂肪),在两个样本中检测到4,4-DDT(平均6.70± 0.42 ng g -1脂肪),3个样品中的2,4'-二氯二苯基二氯乙烯(平均6.27±0.42 ng g -1脂肪),PCB-28六个样品中的(平均10.03±7.79 ng g -1脂肪),一份样品中的PCB-81(7.60 ng g -1脂肪)和一份样品中的PCB-118(10.20 ng g -1的脂肪)。总体上,在农村地区的12名女性中检出了有机氯化合物(40%),在城市女性中检出了12种有机氯化合物(40%)。这些结果表明了研究对象所居住的环境中有机氯化合物的水平。
更新日期:2017-05-17
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