Organochlorine compounds in the adipose tissue of urban and rural women who gave birth by cesarean delivery in northern Turkey,Toxicology Research

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Organochlorine compounds in the adipose tissue of urban and rural women who gave birth by cesarean delivery in northern Turkey
Toxicology Research ( IF 2.2 ) Pub Date : 2017-05-17 00:00:00 , DOI: 10.1039/c7tx00111h
Yavuz Kursad Das ₁ , Davut Guven ₂ , Dilek Guvenc ₁ , Orhan Tokur ₁ , Abdurrahman Aksoy ₁

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In this study, the levels of a group of organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs) in the adipose tissue of women living in northern Turkey who gave birth by cesarean delivery were investigated. Sixty subcutaneous samples were collected in 2013 from women in urban (30) and rural (30) areas. The levels of nine OCPs, namely α-hexachlorocyclohexane (HCH), β-HCH (lindane), γ-HCH, hexachlorobenzene (HCB), aldrin, and dichlorodiphenyltrichloroethane (DDT) and its metabolites, 2,4′-dichlorodiphenyldichloroethylene (DDE), 4,4′-DDE, 2,4′-DDT, 4,4′-DDT, and 16 PCBs, PCB-28, -52, -70, -74, -81, -99, -101, -118, -138, -153, -156, -170, -180, -183, -187 and -208, were investigated with a gas chromatograph equipped with an electron capture detector (GC-ECD). β-HCH was detected in nine samples (mean 23.70 ± 4.24 ng g⁻¹ of fat) and γ-HCH was detected in six samples (mean 41.88 ± 12.41 ng g⁻¹ of fat). HCB was detected in five samples (mean 30.97 ± 14.31 ng g⁻¹ of fat), 2,4′-DDT in one sample (5 ng g⁻¹ of fat), 4,4-DDT in two samples (mean 6.70 ± 0.42 ng g⁻¹ of fat), 2,4′-dichlorodiphenyldichloroethylene in three samples (mean 6.27 ± 0.42 ng g⁻¹ of fat), PCB-28 in six samples (mean 10.03 ± 7.79 ng g⁻¹ of fat), PCB-81 in one sample (7.60 ng g⁻¹ of fat) and PCB-118 in one sample (10.20 ng g⁻¹ of fat). In total, organochlorine compounds were detected in 12 (40%) of rural and 12 (40%) of urban women. These results are an indication of the level of organochlorine compounds in the environment where the subjects of the study lived.

中文翻译：

土耳其北部城乡剖腹产妇女脂肪组织中的有机氯化合物

在这项研究中，对土耳其北部剖腹产妇女的脂肪组织中一组有机氯农药 (OCP) 和多氯联苯 (PCB) 的水平进行了调查。 2013 年，从城市（30 例）和农村（30 例）地区的女性身上采集了 60 份皮下样本。九种 OCP 的含量，即 α-六氯环己烷 (HCH)、β-HCH（林丹）、γ-HCH、六氯苯 (HCB)、艾氏剂和二氯二苯基三氯乙烷 (DDT) 及其代谢物 2,4'-二氯二苯基二氯乙烯 (DDE) 、4,4′-DDE、2,4′-DDT、4,4′-DDT 和 16 PCB、PCB-28、-52、-70、-74、-81、-99、-101、-118 、-138、-153、-156、-170、-180、-183、-187 和 -208，使用配备电子捕获检测器 (GC-ECD) 的气相色谱仪进行研究。在 9 个样品中检测到了 β-六氯环己烷（脂肪平均含量为 23.70 ± 4.24 ng g ^-1 ），在 6 个样品中检测到了 γ-六氯环己烷（脂肪平均含量为 41.88 ± 12.41 ng g ^-1 ）。五个样品中检出六氯苯（脂肪平均含量为 30.97 ± 14.31 ng g ^-1 ），一个样品中检出 2,4'-DDT（脂肪含量为 5 ng g ^-1 ），两个样品中检出 4,4-DDT（脂肪平均值为 6.70 ± 14.31 ng g -1）。 0.42 ng g ^-1脂肪）、三个样品中的 2,4'-二氯二苯基二氯乙烯（脂肪平均含量为 6.27 ± 0.42 ng g ^-1 ）、六个样品中的 PCB-28（脂肪平均含量为 10.03 ± 7.79 ng g ^-1 ），一份样品中含有 PCB-81（7.60 ng g ^-1脂肪），一份样品中含有 PCB-118（10.20 ng g ^-1脂肪）。总共有 12 名（40%）农村妇女和 12 名（40%）城市妇女检出有机氯化合物。这些结果表明了研究对象居住的环境中有机氯化合物的水平。

更新日期：2017-05-17

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