Abstract

Recyclable Pd/C-catalyzed Heck reaction of 2-iodoanilines with acrylate has been developed. The reaction occurred readily in 1,4-dioxane using Pd/C (10 wt%) as catalyst under ligand-free conditions, and the cross-coupling products were obtained with medium to high yield. Gram-scale reactions and recycling of the catalyst were also demonstrated.

Recyclable Pd/C-catalyzed Heck reaction of 2-iodoanilines with acrylate has been developed. The reaction occurred readily in 1,4-dioxane using Pd/C (10 wt%) as catalyst under ligand-free conditions, and the cross-coupling products were obtained with medium to high yield. Gram-scale reactions and recycling of the catalyst were also demonstrated.

中文翻译：

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无配体条件下再生的Pd / C催化2-碘苯胺的Heck反应

摘要

已经开发了2-碘苯胺与丙烯酸酯的可回收的Pd / C催化的Heck反应。在无配体的条件下，使用Pd / C（10 wt％）作为催化剂，在1,4-二恶烷中很容易发生反应，并且以中等至高收率获得了交叉偶联产物。还证明了克级反应和催化剂的再循环。

已经开发了2-碘苯胺与丙烯酸酯的可回收的Pd / C催化的Heck反应。在无配体的条件下，使用Pd / C（10 wt％）作为催化剂，在1,4-二恶烷中很容易发生反应，并且以中等至高收率获得了交叉偶联产物。还证明了克级反应和催化剂的再循环。