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Polysulfobetaine-surfactant solutions and their use in stabilizing hydrophobic compounds in saline solution
Polymer ( IF 4.1 ) Pub Date : 2017-08-28 , DOI: 10.1016/j.polymer.2017.08.057
Jukka Niskanen , Jaana Vapaavuori , Christian Pellerin , Françoise M. Winnik , Heikki Tenhu

A star shaped poly(sulfobetaine methacrylate) (PSBMA) and its linear analogs, display upper-critical-solution-temperature (UCST) type behavior in 0.1 M NaCl. The presence of sodium dodecyl sulfate (SDS) or cetyl trimethyl ammonium bromide (CTAB) has a significant effect on the thermal transition of the polymer. The association of the polymer with the surfactants is confirmed by isothermal titration calorimetry (ITC) and infrared (IR) spectroscopy. SDS forms hydrophobic domains along the polymer chains, preventing the polymers from undergoing a thermal phase transition. These domains can be used to capture 1-anilino-8-naphthalenesulfonate (1,8-ANS), pyrene and curcumin, and increase their fluorescence intensity. Curcumin, which is unstable in aqueous solutions, is stabilized against degradation upon solubilization by the PSBMA-SDS complexes.



中文翻译:

多磺基甜菜碱表面活性剂溶液及其在稳定盐溶液中疏水化合物中的用途

星形聚甲基丙烯酸磺基甜菜碱酯(PSBMA)及其线性类似物在0.1 M NaCl中显示出高临界溶液温度(UCST)类型的行为。十二烷基硫酸钠(SDS)或十六烷基三甲基溴化铵(CTAB)的存在对聚合物的热转变具有重大影响。聚合物与表面活性剂的缔合通过等温滴定热法(ITC)和红外(IR)光谱进行确认。SDS沿聚合物链形成疏水域,从而防止聚合物发生热相变。这些结构域可用于捕获1-苯胺基-8-萘磺酸盐(1,8-ANS),pyr和姜黄素,并增加其荧光强度。姜黄素在水溶液中不稳定,可通过PSBMA-SDS复合物溶解后稳定下来,以防降解。

更新日期:2017-08-28
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