The Ran-binding protein microtubule-organizing center (RanBPM) is a highly conserved nucleocytoplasmic protein involved in a variety of intracellular signaling pathways that control diverse cellular functions. RanBPM interacts with proteins that are linked to various diseases, including Alzheimer’s disease (AD), schizophrenia (SCZ), and cancer. In this article, we define the characteristics of the scaffolding protein RanBPM and focus on its interaction partners in diverse physiological disorders, such as neurological diseases, fertility disorders, and cancer.

中文翻译：

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RanBPM：调节多种生理疾病的潜在治疗靶标

Ran结合蛋白微管组织中心（RanBPM）是一种高度保守的核质蛋白，涉及控制多种细胞功能的多种细胞内信号通路。RanBPM与与多种疾病（包括阿尔茨海默氏病（AD），精神分裂症（SCZ）和癌症）相关的蛋白质相互作用。在本文中，我们定义了支架蛋白RanBPM的特征，并着眼于其在各种生理疾病（如神经系统疾病，生育力障碍和癌症）中的相互作用伙伴。