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Point-of-care C-reactive protein-based tuberculosis screening for people living with HIV: a diagnostic accuracy study.
The Lancet ( IF 98.4 ) Pub Date : 2017-12-01 , DOI: 10.1016/s1473-3099(17)30488-7
Christina Yoon , Fred C Semitala , Elly Atuhumuza , Jane Katende , Sandra Mwebe , Lucy Asege , Derek T Armstrong , Alfred O Andama , David W Dowdy , J Luke Davis , Laurence Huang , Moses Kamya , Adithya Cattamanchi

Symptom-based screening for tuberculosis is recommended for all people living with HIV. This recommendation results in unnecessary Xpert MTB/RIF testing in many individuals living in tuberculosis-endemic areas and thus poor implementation of intensified case finding and tuberculosis preventive therapy. Novel approaches to tuberculosis screening are needed to help achieve global targets for tuberculosis elimination. We assessed the performance of C-reactive protein (CRP) measured with a point-of-care assay as a screening tool for active pulmonary tuberculosis.

中文翻译:

针对艾滋病毒感染者的即时护理基于C反应蛋白的结核病筛查:诊断准确性研究。

建议所有艾滋病毒感染者进行基于症状的结核病筛查。该建议导致许多居住在结核病流行地区的人不必要的Xpert MTB / RIF测试,因此强化病例发现和结核病预防治疗的实施不力。需要新的结核病筛查方法,以帮助实现消除结核病的全球目标。我们评估了即时诊断法作为活动性肺结核筛查工具的C反应蛋白(CRP)的性能。
更新日期:2017-08-26
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