Activation of the receptor interacting serine/threonine kinase (RIPK) 3 mediates an inflammatory type of cell death called necroptosis; in addition, RIPK3 has necroptosis-independent roles in inflammation, although these are not well defined. In a recent study published in Cell, Daniels and colleagues demonstrate that RIPK3 controls West Nile virus infection by promoting neuroinflammation in the central nervous system without affecting neuronal death.

中文翻译：

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RIPped用于神经炎症。

受体相互作用的丝氨酸/苏氨酸激酶（RIPK）3的激活介导了一种炎症类型的细胞死亡，称为坏死。此外，RIPK3在炎症中具有与坏死病无关的作用，尽管这些作用尚未明确定义。在Cell上发表的最新研究中，Daniels及其同事证明RIPK3通过促进中枢神经系统中的神经发炎而不影响神经元死亡来控制西尼罗河病毒感染。