The osteosarcoma genome has long been known to be complex, with few common features between tumours. However, a growing number of somatic genome studies, including a recent study by Behjati et al., have identified common themes in subsets of these cancers. The data suggest that subsets of somatic signatures could be therapeutically tractable targets.

中文翻译：

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骨癌：骨肉瘤基因组是否可靶向？

众所周知，骨肉瘤的基因组很复杂，肿瘤之间几乎没有共同特征。但是，越来越多的体细胞基因组研究，包括Behjati等人的最新研究，已经确定了这些癌症子集中的共同主题。数据表明，体细胞签名的子集可能是治疗上容易治疗的靶标。