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Bone cancer: Is the osteosarcoma genome targetable?
Nature Reviews Endocrinology ( IF 31.0 ) Pub Date : 2017-08-04 , DOI: 10.1038/nrendo.2017.101
Sharon A. Savage , Lisa Mirabello

The osteosarcoma genome has long been known to be complex, with few common features between tumours. However, a growing number of somatic genome studies, including a recent study by Behjati et al., have identified common themes in subsets of these cancers. The data suggest that subsets of somatic signatures could be therapeutically tractable targets.

中文翻译:

骨癌:骨肉瘤基因组是否可靶向?

众所周知,骨肉瘤的基因组很复杂,肿瘤之间几乎没有共同特征。但是,越来越多的体细胞基因组研究,包括Behjati等人的最新研究,已经确定了这些癌症子集中的共同主题。数据表明,体细胞签名的子集可能是治疗上容易治疗的靶标。
更新日期:2017-08-24
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