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Learning in the Rodent Motor Cortex
Annual Review of Neuroscience ( IF 12.1 ) Pub Date : 2017-08-03 00:00:00 , DOI: 10.1146/annurev-neuro-072116-031407
Andrew J Peters 1, 2 , Haixin Liu 1 , Takaki Komiyama 1
Affiliation  

The motor cortex is far from a stable conduit for motor commands and instead undergoes significant changes during learning. An understanding of motor cortex plasticity has been advanced greatly using rodents as experimental animals. Two major focuses of this research have been on the connectivity and activity of the motor cortex. The motor cortex exhibits structural changes in response to learning, and substantial evidence has implicated the local formation and maintenance of new synapses as crucial substrates of motor learning. This synaptic reorganization translates into changes in spiking activity, which appear to result in a modification and refinement of the relationship between motor cortical activity and movement. This review presents the progress that has been made using rodents to establish the motor cortex as an adaptive structure that supports motor learning.

中文翻译:



啮齿动物运动皮层的学习



运动皮层远不是运动命令的稳定渠道,而是在学习过程中经历了显着的变化。使用啮齿类动物作为实验动物,对运动皮层可塑性的理解得到了极大的提高。这项研究的两个主要焦点是运动皮层的连接性和活动。运动皮层表现出响应学习的结构变化,大量证据表明新突触的局部形成和维持是运动学习的重要基础。这种突触重组转化为尖峰活动的变化,这似乎导致运动皮层活动和运动之间关系的修改和细化。这篇综述介绍了利用啮齿类动物建立运动皮层作为支持运动学习的适应性结构所取得的进展。

更新日期:2017-08-03
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