A palladium-catalyzed conjugate addition of arylboronic acids to α-substituted cyclic enones was developed to give α,β-disubstituted ketones with high diastereoselectivity. Mechanistic investigation showed that the high diastereoselectivity was realized through epimerization.

中文翻译：

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非对映选择性钯催化的芳基硼酸与α-取代的环烯酮的共轭加成

开发了钯催化的芳基硼酸与 α-取代环烯酮的共轭加成，以得到具有高非对映选择性的 α,β-二取代酮。机理研究表明，高非对映选择性是通过差向异构化实现的。