Point-of-care diagnostics to improve maternal and neonatal health in low-resource settings,Lab on a Chip

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Point-of-care diagnostics to improve maternal and neonatal health in low-resource settings
Lab on a Chip ( IF 6.1 ) Pub Date : 2017-08-10 00:00:00 , DOI: 10.1039/c7lc00374a
Catherine E. Majors _{1,

2,

3,

4} , Chelsey A. Smith _{1,

2,

3,

4} , Mary E. Natoli _{1,

2,

3,

4} , Kathryn A. Kundrod _{1,

2,

3,

4} , Rebecca Richards-Kortum _{1,

2,

3,

4}

Affiliation

Each day, approximately 830 women and 7400 newborns die from complications during pregnancy and childbirth. Improving maternal and neonatal health will require bringing rapid diagnosis and treatment to the point of care in low-resource settings. However, to date there are few diagnostic tools available that can be used at the point of care to detect the leading causes of maternal and neonatal mortality in low-resource settings. Here we review both commercially available diagnostics and technologies that are currently in development to detect the leading causes of maternal and neonatal mortality, highlighting key gaps in development where innovative design could increase access to technology and enable rapid diagnosis at the bedside.

中文翻译：

护理点诊断可在资源贫乏地区改善孕产妇和新生儿健康

每天，大约有830名妇女和7400名新生儿死于妊娠和分娩期间的并发症。要改善孕产妇和新生儿的健康状况，就需要在资源贫乏的地区将快速的诊断和治疗带到护理点。但是，迄今为止，在资源匮乏的情况下，几乎没有可用的诊断工具可用于在护理时检测孕产妇和新生儿死亡率的主要原因。在这里，我们回顾了目前正在开发的可用于诊断孕妇和新生儿死亡率的主要原因的商业化诊断方法和技术，突出了开发中的主要差距，在这些差距中，创新设计可以增加对技术的获取并在床边进行快速诊断。

更新日期：2017-08-23

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