The findings of a large prospective cohort study involving 9,856 women with BRCA1 or BRCA2 mutations indicate a 72% cumulative lifetime risk of breast cancer in those harbouring a BRCA1 mutation and a 69% risk for those harbouring a BRCA2 mutation.

中文翻译：

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遗传学：BRCA -mutant乳腺癌/卵巢癌透露

一项涉及9,856名具有BRCA1或BRCA2突变的女性的大型前瞻性队列研究的结果表明，在携带BRCA1突变的女性中，乳腺癌的终生累积风险为72％，而携带BRCA2突变的女性为69％。