Regular biopsy sampling enables the personalized management of patients with metastatic castration-resistant prostate cancer (mCRPC); however, such sampling is invasive, carries the risk of complications, and might fail to capture all of the specific characteristics of a patient's disease. Now, a systematic comparison of matched

中文翻译：

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前列腺癌：ctDNA突变反映了转移性疾病的特征

定期的活检取样可以对转移性去势抵抗性前列腺癌（mCRPC）的患者进行个性化管理；然而，这种采样是侵入性的，具有并发症的风险，并且可能无法捕获患者疾病的所有特定特征。现在，系统地比较匹配