Antioxidants from natural sources, such as vegetables and fruits, are attracting more and more interest. In this work, we evaluated the antioxidant potential of Folium Artemisia Argyi, a traditional Chinese herb medicine and food supplement. The total phenolic content, total flavonoid content, and antioxidant ability of the crude extracts and fractions obtained from consecutively partition of n-hexane, ethyl acetate, and n-butanol were measured and compared. Ethyl acetate fraction shows the highest total phenolic and flavonoid contents and highest antioxidant capability with regard to DPPH, ABTS, superoxide anion free radical scavenging ability, and ferric-reducing antioxidant power. In addition, the potential antioxidant components were screened by DPPH–UHPLC–MS experiments and subsequently characterized by using high-resolution tandem mass spectrometry. This work finally identified 45 antioxidants, including organic acids, phenolic compounds, flavonoids, and methoxylated flavonoids. The results suggested that Folium Artemisiae Argyi is a potential inexpensive resource of natural antioxidants.

来自自然来源的抗氧化剂，例如蔬菜和水果，越来越引起人们的关注。在这项工作中，我们评估了中草药和食品补充剂大叶蒿的抗氧化潜力。的总酚含量，总黄酮含量，粗提取物和从连续分区获得的级分的抗氧化能力Ñ己烷，乙酸乙酯，和Ñ丁醇测量和比较。相对于DPPH，ABTS，超氧化物阴离子自由基清除能力和还原三氧化三铁的能力，乙酸乙酯级分显示出最高的总酚和类黄酮含量和最高的抗氧化能力。此外，DPPH筛选了潜在的抗氧化剂成分–UHPLC–MS实验，然后使用高分辨率串联质谱进行表征。这项工作最终确定了45种抗氧化剂，包括有机酸，酚类化合物，类黄酮和甲氧基化类黄酮。结果表明，青蒿叶是天然抗氧化剂的潜在廉价来源。