Important biological questions can be addressed by interrogating the transcriptomes of cancer cells. In a recently published landmark study, Giustacchini and collaborators used a single-cell approach to analyse mRNA of cancer cells derived from patients with chronic myeloid leukaemia. Herein, we discuss how this approach could be used to address relevant clinical questions.

中文翻译：

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遗传学：将单细胞转录组学带到床边

重要的生物学问题可以通过询问癌细胞的转录组来解决。在最近发表的具有里程碑意义的研究中，朱斯塔奇奇尼（Giustacchini）和合作者使用单细胞方法分析了患有慢性髓性白血病患者的癌细胞的mRNA。本文中，我们讨论了如何将该方法用于解决相关的临床问题。