The risk of T-cell fractricide, a situation in which chimeric antigen receptor (CAR) T cells are toxic to each other, owing to the expression of multiple shared antigens by malignant and nonmalignant cells, precludes the use of CAR T-cell-based therapies in patients with T-cell malignancies.

中文翻译：

---

血液系统癌症：CD7的基因组破坏可避免杀虫剂

由于恶性和非恶性细胞表达多种共享抗原，因此嵌合抗原受体（CAR）T细胞彼此有毒性的情况下，T细胞杀虫剂的风险会阻止使用基于CAR T细胞的杀伤剂T细胞恶性肿瘤的治疗。