Abstract

Chiral separation has always been a topic concerned by chemical and pharmaceutical communities. Hybrid organic-inorganic materials (HOIM), with high mechanical stability, large surface area, tailored pore size, controlled morphology and organic loading have shown superior chiral recognition performance in several kinds of chiral separation technologies. In this review, application progress of HOIM used as chiral stationary phases for HPLC, CEC/CLC and GC was discussed in detail. The developments of HOIM applied in membrane separation and electrochemistry discrimination were also summarized.

中文翻译：

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有机-无机杂化材料在手性分离中的应用

摘要

手性分离一直是化学和制药界关注的话题。具有高的机械稳定性，较大的表面积，定制的孔径，可控的形态和有机负荷的混合有机-无机材料（HOIM）在多种手性分离技术中均显示出优异的手性识别性能。在这篇综述中，详细讨论了HOIM用作HPLC，CEC / CLC和GC的手性固定相的应用进展。总结了HOIM在膜分离和电化学判别中的应用进展。