Abstract

Infectious diseases represent a major global threat accounting for one of the leading causes of global mortality and morbidity. Prompt diagnosis of infectious diseases is a crucial first step in the management of infectious threats, which aims to quarantine infected patients to avoid contacts with healthy individuals and deliver effective treatments prior to further spread of diseases. This review article discusses the current advances of diagnostic systems using colloidal nanomaterials (e.g., gold nanoparticles, quantum dots, magnetic nanoparticles) for identifying and differentiating infectious pathogens. The challenges involved in the clinical translation of these emerging nanotechnology based diagnostic devices will also be discussed.

中文翻译：

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使用胶体纳米材料诊断传染性病原体的现状

摘要

传染病是全球主要威胁，是全球死亡和发病的主要原因之一。及时诊断传染病是管理传染病威胁的关键第一步，旨在隔离受感染的患者，避免与健康人接触，并在疾病进一步传播之前提供有效的治疗。这篇综述文章讨论了使用胶体纳米材料（例如金纳米颗粒、量子点、磁性纳米颗粒）来识别和区分传染性病原体的诊断系统的当前进展。还将讨论这些基于纳米技术的新兴诊断设备的临床转化所面临的挑战。