Concise syntheses of the polyketide natural product (–)-muricatacin and (–)-( R , R )-L-factor (natural product enantiomer) were achieved in four steps by employing an organocatalytic asymmetric direct vinylogous aldol reaction of γ-crotonolactone and suitable aliphatic aldehydes as the key step.

中文翻译：

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(-)-Muricatacin 和 (-)-(R,R)-L-Factor 的合成涉及有机催化直接 Vinylogous Aldol 反应

聚酮化合物天然产物 (-)-muricatacin 和 (-)-( R , R )-L-因子（天然产物对映异构体）的简明合成是通过采用 γ-巴豆内酯和合适的脂肪醛作为关键步骤。