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Kinetochore regulation: Let there be light
Nature Chemical Biology ( IF 14.8 ) Pub Date : 2017-08-14 00:00:00 , DOI: 10.1038/nchembio.2464
Ana C Figueiredo 1 , Helder Maiato 2
Affiliation  

Kinetochores form the critical interface with spindle microtubules that accounts for chromosome movement and segregation fidelity during mitosis. Spatial and temporal control of motor protein and checkpoint signaling at kinetochores is now possible with a new set of optogenetic tools.

中文翻译:

动粒调节:要有光

动粒与纺锤体微管形成关键界面,负责有丝分裂过程中的染色体运动和分离保真度。现在,通过一套新的光遗传学工具,可以对动粒的运动蛋白和检查点信号进行空间和时间控制。
更新日期:2017-09-08
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