Abstract

In this review is presented the results of investigations during the last two decades on molecular recognition processes, mainly chiral host–guest systems insofar as they deal with intermolecular recognition events. Attention is devoted to those systems involving chiral hosts whose chirality does not arise from the presence of a chiral center and that possess a defined cavity to accommodate guests. Thus, the scope of this short review is restricted to chiral containers in which size, shape, and functionality are critical aspects, while those examples involving chirality transfer processes are excluded. The systems covered are those with axial chirality, including helical chirality, in which the chirality, that can be inherent or induced by steric interactions, originates from the 3D helical array of substituents. More specifically, the focus is on both macrocycles that bear open cavities and molecular cages with more enclosed voids.

1 Introduction

2 Encapsulating Agents: Macrocycles

3 Encapsulating Agents: Molecular Cages

4 Conclusions

In this review is presented the results of investigations during the last two decades on molecular recognition processes, mainly chiral host–guest systems insofar as they deal with intermolecular recognition events. Attention is devoted to those systems involving chiral hosts whose chirality does not arise from the presence of a chiral center and that possess a defined cavity to accommodate guests. Thus, the scope of this short review is restricted to chiral containers in which size, shape, and functionality are critical aspects, while those examples involving chirality transfer processes are excluded. The systems covered are those with axial chirality, including helical chirality, in which the chirality, that can be inherent or induced by steric interactions, originates from the 3D helical array of substituents. More specifically, the focus is on both macrocycles that bear open cavities and molecular cages with more enclosed voids.

1 Introduction

2 Encapsulating Agents: Macrocycles

3 Encapsulating Agents: Molecular Cages

4 Conclusions

中文翻译：

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轴向手性形状持久性密封剂

摘要

在本综述中，我们介绍了过去二十年来有关分子识别过程的调查结果，这些过程主要是手性宿主-客体系统，涉及分子间识别事件。注意力集中在那些涉及手性宿主的系统上，这些系统的手性不是由手性中心的存在引起的，并且具有确定的容纳客体的空腔。因此，本篇简短综述的范围限于尺寸，形状和功能至关重要的手性容器，而那些涉及手性转移过程的示例则被排除在外。涵盖的系统是具有轴向手性（包括螺旋手性）的系统，其中可以由空间相互作用固有或诱发的手性源自取代基的3D螺旋阵列。进一步来说，

1引言

2封装剂：宏周期

3种封装剂：分子笼

4。结论

在本综述中，我们介绍了过去二十年来有关分子识别过程的调查结果，这些过程主要是手性宿主-客体系统，涉及分子间识别事件。注意力集中在那些涉及手性宿主的系统上，这些系统的手性不是由手性中心的存在引起的，并且具有确定的容纳客体的空腔。因此，本篇简短综述的范围限于尺寸，形状和功能至关重要的手性容器，而那些涉及手性转移过程的示例则被排除在外。涵盖的系统是具有轴向手性（包括螺旋手性）的系统，其中可以由空间相互作用固有或诱发的手性源自取代基的3D螺旋阵列。进一步来说，

1引言

2封装剂：宏周期

3种封装剂：分子笼

4。结论