A major goal in the management of chronic obstructive pulmonary disease (COPD) is to reduce exacerbations. Exacerbations are associated with increased mortality,^1,2 worsened quality of life,³ and accelerated decline in lung function;⁴ making efforts to prevent these effects a worthy treatment goal. The landmark ECLIPSE study⁵ identified a group of patients with at least two exacerbations per year, which were classified as the frequent exacerbator phenotype. Since then, there has been a concerted effort to aggressively treat these patients in an effort to reduce exacerbations and improve outcomes.

中文翻译：

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COPD急性发作表型：重新评估的时间？

慢性阻塞性肺疾病（COPD）管理的主要目标是减少病情加重。病情加重与死亡率增加，^1,2，生活质量下降，³和肺功能加速下降有关；⁴努力防止这些影响成为值得治疗的目标。具有里程碑意义的ECLIPSE研究⁵鉴定了一组每年至少发作两次的患者，这些患者被归类为频繁发作的表型。从那时起，人们就齐心协力积极治疗这些患者，以减少病情加重和改善预后。