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Plasma proteome analysis in patients with pulmonary arterial hypertension: an observational cohort study.
The Lancet ( IF 98.4 ) Pub Date : 2017-09-01 , DOI: 10.1016/s2213-2600(17)30161-3
Christopher J Rhodes 1 , John Wharton 1 , Pavandeep Ghataorhe 1 , Geoffrey Watson 1 , Barbara Girerd 2 , Luke S Howard 3 , J Simon R Gibbs 3 , Robin Condliffe 4 , Charles A Elliot 4 , David G Kiely 4 , Gerald Simonneau 2 , David Montani 2 , Olivier Sitbon 2 , Henning Gall 5 , Ralph T Schermuly 5 , H Ardeschir Ghofrani 5 , Allan Lawrie 6 , Marc Humbert 2 , Martin R Wilkins 1
Affiliation  

Idiopathic and heritable pulmonary arterial hypertension form a rare but molecularly heterogeneous disease group. We aimed to measure and validate differences in plasma concentrations of proteins that are associated with survival in patients with idiopathic or heritable pulmonary arterial hypertension to improve risk stratification.

中文翻译:

肺动脉高压患者的血浆蛋白质组分析:一项观察性队列研究。

特发性和遗传性肺动脉高压形成了一种罕见但分子异质的疾病组。我们旨在测量和验证与特发性或遗传性肺动脉高压患者的生存相关的蛋白质血浆浓度差异,以改善风险分层。
更新日期:2017-08-10
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