Delirium in critically ill patients is complex and challenging to capture; its identification is mostly based on imperfect screening tools rather than clinical diagnosis, and the effects of baseline frailty, drug exposure, and delirium severity, and the outcomes attributable to delirium, make monitoring of these variables, and evaluation of treatment, difficult. No pharmacological management has proven effective in delirium prevention or treatment. Systemic inflammation, however, has been linked to delirium.

中文翻译：

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ir妄中他汀类药物的试验-被复杂的方法所困扰吗？

重症患者的妄非常复杂且难以捕获。其鉴别主要是基于不完善的筛查工具而不是临床诊断，并且基线虚弱，药物暴露和ir妄的严重性以及del妄可归因的结果使监测这些变量和评估治疗变得困难。在del妄的预防或治疗中，没有药理管理方法被证明是有效的。然而，全身性炎症与del妄有关。