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Comparative effectiveness of high-dose versus standard-dose influenza vaccination on numbers of US nursing home residents admitted to hospital: a cluster-randomised trial.
The Lancet ( IF 168.9 ) Pub Date : 2017-09-01 , DOI: 10.1016/s2213-2600(17)30235-7
Stefan Gravenstein , H Edward Davidson , Monica Taljaard , Jessica Ogarek , Pedro Gozalo , Lisa Han , Vincent Mor

Immune responses to influenza vaccines decline with age, reducing clinical effectiveness. We compared the effect of the more immunogenic high-dose trivalent influenza vaccine with a standard-dose vaccine to identify the effect on reducing hospital admissions of nursing home residents in the USA.

中文翻译:

大剂量流感疫苗和标准剂量流感疫苗接种对住院美国美国疗养院居民数量的比较有效性:一项整群随机试验。

对流感疫苗的免疫反应会随着年龄的增长而下降,从而降低了临床效果。我们将更具免疫原性的高剂量三价流感疫苗与标准剂量疫苗的效果进行了比较,以确定在减少美国疗养院居民住院方面的效果。
更新日期:2017-08-10
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