Researchers are now harvesting the first fruits of their labour from nearly two decades of tremendous efforts to track progression of Huntington's disease in the manifest and premanifest phases. Large observational studies such as PREDICT-HD,¹ COHORT,² REGISTRY,³ and TRACK-HD⁴ have aimed to find objective measures of disease progression and learn about the course of the disease. The work to measure disease progression is ongoing. The global, observational study ENROLL-HD⁵ is currently recruiting and is intended to become the largest study of Huntington's disease.

中文翻译：

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识别亨廷顿氏病进展的调节剂

现在，研究人员正在通过将近二十年的巨大努力来收获他们的劳动成果，以追踪明显阶段和预演阶段的亨廷顿氏病进展。大型观察性研究，例如PREDICT-HD，¹ COHORT，² REGISTRY，³和TRACK-HD ⁴，旨在发现疾病进展的客观指标并了解疾病的进程。测量疾病进展的工作正在进行中。目前正在招募全球性的观察性研究ENROLL-HD ⁵，该研究旨在成为亨廷顿氏病的最大研究。