Tremor is the most common disorder in patients with multiple sclerosis and greatly contributes to the disability of these patients. This tremor rarely presents with the high-frequency action component seen in primary tremor disorders; rather, it is the combination of several features, particularly cerebellar ones. Therefore, drugs are rarely effective, whereas surgery can provide variable results depending on the severity of the underlying ataxia. In The Lancet Neurology, Seth Oliveria and colleagues¹ report the findings from their single centre, single-blind, prospective, randomised pilot trial of dual-lead thalamic deep brain stimulation (DBS) in 12 patients with treatment-refractory tremor caused by multiple sclerosis.

中文翻译：

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多发性硬化症性震颤：技术进步是否足够？

震颤是多发性硬化症患者中最常见的疾病，极大地导致了这些患者的残疾。这种震颤很少表现出原发性震颤障碍中的高频作用成分。而是几个特征的结合，特别是小脑的特征。因此，药物很少有效，而根据潜在的共济失调的严重程度，手术可以提供不同的结果。在《柳叶刀神经病学》中，Seth Oliveria及其同事¹报告了他们的双中心丘脑深部脑刺激（DBS）单中心，单盲，前瞻性，随机试验研究的结果，该研究针对12例由多发性硬化引起的难治性震颤患者。