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Shaping and Reshaping Transcriptome Plasticity during Evolution
Trends in Biochemical Sciences ( IF 13.8 ) Pub Date : 2017-07-14 , DOI: 10.1016/j.tibs.2017.06.009 Shobbir Hussain
中文翻译:
在进化过程中塑造和重塑转录组可塑性。
更新日期:2017-07-14
Trends in Biochemical Sciences ( IF 13.8 ) Pub Date : 2017-07-14 , DOI: 10.1016/j.tibs.2017.06.009 Shobbir Hussain
Transcriptome plasticity, usually associated with alternative isoform generation, is recognised as a key mechanism driving proteomic diversity and biological complexity. Recent findings of Liscovitch-Brauer et al. and Ma et al. suggest that RNA base modifications are an additional central mode of transcriptome malleability that have the potential to determine evolutionary outcomes.
中文翻译:
在进化过程中塑造和重塑转录组可塑性。
转录组可塑性通常与替代同工型产生有关,被认为是驱动蛋白质组学多样性和生物学复杂性的关键机制。Liscovitch-Brauer等人的最新发现。和Ma等。提示RNA碱基修饰是转录组延展性的另一种主要模式,具有决定进化结果的潜力。