To the Editor The outstanding individual participant data meta-analysis by Karyotaki and colleagues¹ highlights the efficacy of self-guided internet-based interventions for depressive symptoms, thereby making the case for the use of individual participant data meta-analysis as a gold standard for evidence-based mental health care. However, the discussion would have benefited from a more differentiated point of view regarding the clinical significance of their findings.

中文翻译：

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常规护理中基于互联网的抑郁症自助干预

致编辑Karyotaki 及其同事¹出色的个人参与者数据荟萃分析强调了基于互联网的自我指导干预对抑郁症状的疗效，从而将个人参与者数据荟萃分析用作治疗抑郁症的黄金标准。以证据为基础的精神卫生保健。然而，讨论将受益于关于他们发现的临床意义的更加不同的观点。