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Engineered Cpf1 variants with altered PAM specificities
Nature Biotechnology ( IF 33.1 ) Pub Date : 2017-06-05 00:00:00 , DOI: 10.1038/nbt.3900 Linyi Gao , David B T Cox , Winston X Yan , John C Manteiga , Martin W Schneider , Takashi Yamano , Hiroshi Nishimasu , Osamu Nureki , Nicola Crosetto , Feng Zhang
Nature Biotechnology ( IF 33.1 ) Pub Date : 2017-06-05 00:00:00 , DOI: 10.1038/nbt.3900 Linyi Gao , David B T Cox , Winston X Yan , John C Manteiga , Martin W Schneider , Takashi Yamano , Hiroshi Nishimasu , Osamu Nureki , Nicola Crosetto , Feng Zhang
The targeting range of the CRISPR endonuclease Cpf1 is increased three-fold by molecular engineering.
中文翻译:
经过改造的Cpf1变体,其PAM特异性发生了变化
CRISPR核酸内切酶Cpf1的靶向范围通过分子工程技术提高了三倍。
更新日期:2017-08-09
中文翻译:
经过改造的Cpf1变体,其PAM特异性发生了变化
CRISPR核酸内切酶Cpf1的靶向范围通过分子工程技术提高了三倍。