Interest in the development of new hybrid materials based on natural polysaccharides has grown exponentially in the last decade. Such materials are commonly obtained by the graft modification of polysaccharides via reversible deactivation radical polymerization (RDRP). Research has focused on the use of RDRP techniques, including ATRP (atom transfer radical polymerization), NMP (nitroxide-mediated polymerization) and RAFT (reversible addition–fragmentation chain transfer polymerization), not only because of the good control over the molecular weight distribution that RDRP provides, but also because of the complex macromolecular architectures that can be achieved. This review highlights the most recent development, challenges, uses and applications of the polymer graft modification of several common natural polysaccharides (chitin, chitosan, alginate, dextran, starch and cellulose derivatives) via RDRP.

在过去的十年中，对开发基于天然多糖的新型杂化材料的兴趣成倍增长。通常通过可逆的失活自由基聚合（RDRP）通过对多糖进行接枝改性来获得此类材料。研究集中在RDRP技术的使用上，包括ATRP（原子转移自由基聚合），NMP（氮氧化物介导的聚合）和RAFT（可逆加成-断裂链转移聚合），这不仅是因为可以很好地控制分子量分布RDRP所提供的，也是因为可以实现复杂的大分子体系结构。这篇评论重点介绍了几种常见天然多糖（几丁质，壳聚糖，