Vitamin E family members: tocotrienols and tocopherols are widely known for their health benefits. Decades of research on tocotrienols have shown they have diverse biological activities such as antioxidant, anti-inflammatory, anticancer, neuroprotective and skin protection benefits, as well as improved cognition, bone health, longevity and reduction of cholesterol levels in plasma. Tocotrienols also modulate several intracellular molecular targets and, most importantly, have been shown to improve lipid profiles, reduce total cholesterol and reduce the volume of white matter lesions in human clinical trials. This review provides a comprehensive update on the little-known therapeutic potentials of tocotrienols, which tocopherols lack in a variety of inflammation-driven diseases.

维生素E家庭成员：生育三烯酚和生育酚以其健康益处而广为人知。数十年来对生育三烯酚的研究表明，它们具有多种生物活性，例如抗氧化剂，抗炎剂，抗癌剂，神经保护剂和皮肤保护剂，以及认知功能改善，骨骼健康，寿命长和血浆胆固醇水平降低。生育三烯酚还可以调节一些细胞内分子靶标，最重要的是，在人类临床试验中，生育三烯酚还可以改善脂质分布，降低总胆固醇并减少白质病变的体积。这篇综述提供了生育三烯酚的鲜为人知的治疗潜力的全面更新，生育三烯酚缺乏多种炎症驱动性疾病。