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Triflic Anhydride Promoted Intramolecular Cyclization of N-Aryl Cinnamides: Access to Polysubstituted Quinolin-2(1H)-ones
Synthesis ( IF 2.6 ) Pub Date : 2017-08-02 , DOI: 10.1055/s-0036-1590821 Rui Zhang , Dewen Dong , Qian Zhang , Jingwen Yuan , Mangfei Yu , Yongjiu Liang , Peng Huang
中文翻译:
Triflic酸酐促进N-芳基肉桂酸酯的分子内环化:访问多取代的喹啉2(1H)-一。
更新日期:2017-08-02
Synthesis ( IF 2.6 ) Pub Date : 2017-08-02 , DOI: 10.1055/s-0036-1590821 Rui Zhang , Dewen Dong , Qian Zhang , Jingwen Yuan , Mangfei Yu , Yongjiu Liang , Peng Huang
Abstract
A facile and efficient synthesis of polysubstituted quinolin-2(1H)-ones is developed via intramolecular cyclization of readily available N-aryl cinnamides promoted by triflic anhydride in N,N-dimethyl trifluoroacetamide (DTA) under mild conditions.
A facile and efficient synthesis of polysubstituted quinolin-2(1H)-ones is developed via intramolecular cyclization of readily available N-aryl cinnamides promoted by triflic anhydride in N,N-dimethyl trifluoroacetamide (DTA) under mild conditions.
中文翻译:
Triflic酸酐促进N-芳基肉桂酸酯的分子内环化:访问多取代的喹啉2(1H)-一。
摘要
通过在温和的条件下在N,N-二甲基三氟乙酰胺(DTA)中由三氟甲磺酸酐促进的易于获得的N-芳基肉桂酸酯的分子内环化作用,开发了一种简便,有效的多取代喹啉2(1 H)-酮合成方法。
通过在温和的条件下在N,N-二甲基三氟乙酰胺(DTA)中由三氟甲磺酸酐促进的易于获得的N-芳基肉桂酸酯的分子内环化作用,开发了一种简便,有效的多取代喹啉2(1 H)-酮合成方法。