This commentary highlights the findings by Tao et al. (Theranostics 2016; 6: 2068-2083) that targeting miR-433 may be a potential therapeutic strategy for myocardial fibrosis and subsequently discusses the obstacles and prospects associated with the application of therapeutic microRNAs in anti-fibrosis treatment.

中文翻译：

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调节microRNA作为心脏纤维化的新型治疗靶标

该评论强调了Tao等人的发现。（Theranostics 2016; 6：2068-2083），靶向miR-433可能是心肌纤维化的潜在治疗策略，随后讨论了与治疗性microRNA在抗纤维化治疗中应用相关的障碍和前景。