Abstract

2-Hydroxyindan-1-ones have been efficiently synthesized and successfully applied as ligands in Pd-catalyzed Ullmann type, Suzuki–Miyaura, and Mizoroki–Heck cross-coupling reactions with aryl tosylates and aryl halides. The ligands are air- and moisture-stable and have shown high catalytic activity with Pd(OAc)₂ in these cross-coupling reactions. The system tolerates a variety of functional groups in the product and can be re-used at least three times with maximum efficiency.

2-Hydroxyindan-1-ones have been efficiently synthesized and successfully applied as ligands in Pd-catalyzed Ullmann type, Suzuki–Miyaura, and Mizoroki–Heck cross-coupling reactions with aryl tosylates and aryl halides. The ligands are air- and moisture-stable and have shown high catalytic activity with Pd(OAc)₂ in these cross-coupling reactions. The system tolerates a variety of functional groups in the product and can be re-used at least three times with maximum efficiency.

中文翻译：

---

Pd /基于茚满酮的配体：高效的Ullmann型，Suzuki–Miyaura和Mizoroki–Heck交叉偶联反应与芳基甲苯磺酸盐和芳基卤化物的催化剂体系

摘要

2-羟基茚满-1-酮已被有效地合成，并成功地用作Pd催化的Ullmann型，Suzuki-Miyaura和Mizoroki-Heck与芳基甲苯磺酸盐和芳基卤化物的交叉偶联反应的配体。配体是空气和水分稳定的，并且在这些交叉偶联反应中显示出对Pd（OAc）_2的高催化活性。该系统可以承受产品中的各种官能团，并且可以以最高效率至少重复使用3次。

2-羟基茚满-1-酮已被有效地合成，并成功地用作Pd催化的Ullmann型，Suzuki-Miyaura和Mizoroki-Heck与芳基甲苯磺酸盐和芳基卤化物的交叉偶联反应的配体。配体是空气和水分稳定的，并且在这些交叉偶联反应中显示出对Pd（OAc）_2的高催化活性。该系统可以承受产品中的各种官能团，并且可以以最高效率至少重复使用3次。