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Efflux Pumps Might Not Be the Major Drivers of QAC Resistance in Methicillin-Resistant Staphylococcus aureus
ChemBioChem ( IF 3.2 ) Pub Date : 2017-08-01 06:11:55 , DOI: 10.1002/cbic.201700395
Megan C. Jennings 1 , Megan E. Forman 2 , Stephanie M. Duggan 2 , Kevin P. C. Minbiole 2 , William M. Wuest 1, 3
Affiliation  

The inside cover picture shows that cell-membrane composition might be the primary driver of bacterial resistance to quaternary ammonium compounds (QACs). Our findings shed light on this daunting phenomenon with world-wide impact as QACs are ubiquitous in household cleaners and typically serve as the last line of defense in home sanitation. More information can be found in the communication by K. P. C. Minbiole, W. M. Wuest, et al. (DOI: 10.1002/cbic.201700233).

中文翻译:

外排泵可能不是耐甲氧西林金黄色葡萄球菌对QAC耐药的主要驱动力

封面图片显示,细胞膜成分可能是细菌对季铵化合物(QAC)产生抗药性的主要驱动力。我们的发现揭示了这种令人震惊的现象,并在全球范围内产生影响,因为QAC在家庭清洁工中无处不在,通常成为家庭卫生的最后一道防线。在K.P.C.Minbiole,W.M.Wuest等人的来文中可以找到更多信息。(DOI:10.1002 / cbic.201700233)。
更新日期:2017-08-02
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