The lung undergoes a striking repair process in response to severe injuries such as influenza infection. A study now demonstrates that associated stem/progenitor cells are heterogeneous in nature and comprise subpopulations dominated by hypoxia/Notch or Wnt signalling. Modulation of this heterogeneity in favour of functional repair may have therapeutic value.

中文翻译：

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肺修复工具包的起源和规范。

肺对严重的伤害（例如流感感染）进行了惊人的修复过程。现在的一项研究表明，相关的干/祖细胞本质上是异质的，并且包含以缺氧/ Notch或Wnt信号为主的亚群。有利于功能修复的这种异质性调节可能具有治疗价值。