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Hacking DNA copy number for circuit engineering.
Nature Genetics ( IF 30.8 ) Pub Date : 2017-Jul-27 , DOI: 10.1038/ng.3923
Feilun Wu , Lingchong You

DNA copy number represents an essential parameter in the dynamics of synthetic gene circuits but typically is not explicitly considered. A new study demonstrates how dynamic control of DNA copy number can serve as an effective strategy to program robust oscillations in gene expression circuits.

中文翻译:

破解DNA拷贝数以进行电路工程设计。

DNA拷贝数代表了合成基因回路动力学中的一个基本参数,但通常没有明确考虑。一项新的研究表明,DNA拷贝数的动态控制如何可以作为一种有效的策略来编程基因表达电路中的稳健振荡。
更新日期:2017-07-28
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