Functional membrane microdomains (FMMs) serve to spatially restrict and coordinate a diversity of cellular functions. Flotillins serve as scaffolds within FMMs, and in this issue ofCell Chemical Biology,Koch et al. (2017)show that disruptingStaphylococcus aureusscaffolds via small molecules perturbs virulence gene expression and attenuatesS. aureusvirulence.

中文翻译：

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破坏金黄色葡萄球菌的筏：金黄色葡萄球菌不再沉没？

功能性膜微区（FMM）用于在空间上限制和协调细胞功能的多样性。Flotillins用作FMM中的支架，在本期《细胞化学生物学》（Cell Chemical Biology）中，Koch等人 （2017）表明，通过小分子破坏金黄色葡萄球菌支架会扰乱毒力基因表达并减弱S. 金黄色葡萄球菌。