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Catch Shiny Droplets in Suspension—Finding the Needle in a Haystack
Cell Chemical Biology ( IF 8.6 ) Pub Date : 2017-07-20 , DOI: 10.1016/j.chembiol.2017.07.004
Nina V. Hein-Fuchs , Renate König

In a recent issue ofCell Chemical Biology,Chaipan et al. (2017)described a high-throughput screening methodology to identify epitopes on HIV-1 particles recognized by broadly neutralizing antibodies. The approach utilizes a droplet-based microfluidics platform combining robust phenotypic single-virus sorting with next-generation sequencing of viral quasispecies.

中文翻译:

捕捉悬浮的闪亮水滴—在干草堆中寻找针头

在最近一期的《细胞化学生物学》中,Chaipan等人。(2017)描述了一种高通量筛选方法,以鉴定被广泛中和抗体识别的HIV-1颗粒上的表位。该方法利用基于液滴的微流控平台,该平台结合了强大的表型单病毒分选和下一代病毒准种测序。
更新日期:2017-07-22
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