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Expanding the Tissue Toolbox: Deriving Colon Tissue from Human Pluripotent Stem Cells.
Cell Stem Cell ( IF 19.8 ) Pub Date : 2017-07-06 , DOI: 10.1016/j.stem.2017.06.001
Lotte Bruens , Hugo J.G. Snippert

Organoid technology holds great potential for disease modeling and regenerative medicine. In this issue of Cell Stem Cell, Múnera et al. (2017) establish the generation of pluripotent stem cell-derived colon organoids that upon transplantation in mice, resembling human colon to a large extent, opening up avenues to study disease pathogenesis in human colon tissue.

中文翻译:

扩展组织工具箱:从人多能干细胞中提取结肠组织。

类器官技术在疾病建模和再生医学方面具有巨大的潜力。在本期《细胞干细胞》中,Múnera等人。(2017)建立了多能干细胞来源的结肠类器官的生成,该类器官在小鼠移植后在很大程度上类似于人结肠,为研究人结肠组织中的疾病发病机理开辟了道路。
更新日期:2017-07-06
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