A new study shows that aberrant DNA transposase activity promotes structural alterations that are clonally selected to drive tumor development. This discovery uncovers novel mechanisms of tumor-suppressor gene inactivation and highlights a new approach to cancer gene identification.

中文翻译：

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转座酶驱动的人类肿瘤重排。

一项新的研究表明，异常的DNA转座酶活性促进了克隆选择驱动肿瘤发展的结构改变。这一发现揭示了肿瘤抑制基因失活的新机制，并突出了一种用于癌症基因鉴定的新方法。