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Host response: Inflammation promotes TB growth
Nature Microbiology ( IF 28.3 ) Pub Date : 2017-06-27 00:00:00 , DOI: 10.1038/nmicrobiol.2017.102
Christina L. Stallings

Host response: Inflammation promotes TB growth

Nature Microbiology, Published online: 27 June 2017; doi:10.1038/nmicrobiol.2017.102

Nitric oxide synthase has long been associated with control of Mycobacterium tuberculosis infection. However, new work reveals that instead of directing an antibacterial killing response, nitric oxide is critical for restraining granulocytic inflammation, which can provide a nutrient-rich niche for increased bacterial growth.



中文翻译:

宿主反应:炎症促进结核病的增长

宿主反应:炎症促进结核病的增长

《自然微生物学》,在线发布:2017年6月27日; doi:10.1038 / nmicrobiol.2017.102

一氧化氮合酶长期以来一直与结核分枝杆菌感染的控制有关。然而,新的研究表明,一氧化氮不是指导抗菌素的杀灭反应,对抑制粒细胞性炎症至关重要,后者可以提供营养丰富的小生境,以增加细菌的生长。

更新日期:2017-06-28
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