Cytauxzoonosis is an emerging infectious disease that affects wild felids as well as the domestic cat; it is caused by the apicomplexan protozoan parasites belonging to the genus Cytauxzoon. Cytauxzoon felis is the species of major concern, whose transmission occurs via the bite of an infected tick. Cytauxzoonosis of the domestic cat has historically been considered uniformly fatal, with a short course of illness, and most domestic cats die within 9 to 15 days postinfection. However, increasing evidence of domestic cats surviving C. felis infection suggests the existence of different strains with various levels of pathogenicity. Although wild felids are considered natural reservoirs for this parasite, a number of studies suggest that domestic cats that have survived nonlethal infections may serve as an additional reservoir. The current article comprehensively reviews the parasite and its life cycle, geographic distribution, genetic variability, and pathogenesis, as well as host immunology and the diagnosis, treatment, and prevention of infection in the domestic cat. This information should provide a basis for better understanding the parasite as well as the pathogenesis of the disease.

中文翻译：

---

家猫感染猫科动物细胞胞体的两个故事 [评论]


细胞虫病是一种新出现的传染病，影响野生猫科动物和家猫；它是由属于Cytauxzoon属的顶端复门原生动物寄生虫引起的。猫细胞虫是主要关注的物种，其传播是通过受感染蜱虫的叮咬进行的。家猫的细胞虫病历来被认为是致命的，病程较短，大多数家猫在感染后 9 至 15 天内死亡。然而，越来越多的证据表明家猫在猫弯曲菌感染中幸存下来，这表明存在具有不同致病性水平的不同菌株。尽管野生猫科动物被认为是这种寄生虫的天然宿主，但许多研究表明，在非致命性感染中幸存下来的家猫可能是另一个宿主。本文全面综述了寄生虫及其生命周期、地理分布、遗传变异和发病机制，以及宿主免疫学和家猫感染的诊断、治疗和预防。这些信息应该为更好地了解寄生虫以及疾病的发病机制提供基础。